“People taking 2-AEP hardly age, neither in their outward appearance nor by any other criteria like skin tissue elasticity, skeletal firmness, etc.” -Dr. Nieper

Clinical Testing
From approximately 1963 on, we started to apply the primary components of Membrane Integrity Factor™ with the intention of protecting the cell membranes against unwanted intruders. These unwanted intruders can only enter through the so-called free lipid pore of the cell membrane. We presumed, therefore, that the supply of Membrane Integrity Factor™ would have a special sealing function because of the rejective effect of calcium, magnesium and potassium.

Our expectation proved to be correct. In 1971, Monninghoff, Munster, W. Germany, published research demonstrating in a spectacular manner how the sealing of cell membranes with 2-AEP found in Membrane Integrity Factor™ could prevent penetration of 'toxins'.

1967 Study
By 1967, the following results were obtained after administering over 50,000 daily doses. The participants improved considerably as 2-AEP (in Membrane Integrity Factor™) was given in capsule form (approx. 1.5 g. per day) to those with cell membrane damage throughout the body. This membrane damage affects the bone matrix system, the kidneys, the membranes of the pulmonary alveoles, the urinary tract system, the inner linings of little vessels, the membranes of red blood cells as well as many other places.

Furthermore, it was evident that the consequences of unhealthy cell membranes could be drastically reduced, as demonstrated in 1969 by a control group. Likewise, aggressions on cell membranes injected next to the vein could be reduced. Considerable beneficial effects on kidney health were also noted. I reported this in the leading French pharmacodynamic journal Agressologie more than 20 years ago.

Around 1966, the German Health Authority in Berlin approved 2-AEP®.

In 1986-87, Dr. Morrissette conducted a retrospective poll of participants in the USA who originally had begun taking 2-AEP with us in Germany. Just under 300 people were entered in this study showing that 82% of them had had a positive benefit from the 2-AEP (found in Membrane Integrity Factor™). When they had begun taking the 2-AEP in the early stages, this positive result rose to 92%. If they interrupted their dosage, their problems would erupt anew, which was to be expected.

The long-term observation of 2-AEP effect on people in such great numbers produced an entire series of additional, highly relevant phenomenon that are extremely fascinating. First of all, for all practical purposes, people taking 2-AEP hardly age, neither in their outward appearance nor by any other criteria like skin tissue elasticity, skeletal firmness, etc.

In the U.S., some 24 million people suffer from decalcification of the bone system; some 1.45 million experience spontaneous bone fractures every year. In my opinion, there is no alternative to the Calcium 2-AEP® (found in Membrane Integrity Factor™).

On the basis of this observation, research on 2-AEP and bone health have begun. I feel that the energetic membrane impairment in the bone matrix tissue is one of the key factors in bone health. However, supplementation with conventional calcium salts fail.

Success with 2-AEP Increasing Oxygen Intake:
Regular use of Membrane Integrity Factor™ results in supporting lung alveolus cell function, which promote healthy breathing.

A few weeks after beginning therapy with 2-AEP (found in Membrane Integrity Factor™), negative breathing reactions will subside and almost disappear.

Success With Blood Energy Levels
During the late 1960’s and early 1970’s, we noticed that people enjoyed the benefits of Longevity for maintaining healthy blood sugar levels already within the normal range. The metabolism improved, tolerance to sugar improved, and the kidneys especially appeared to react favorably to the 2-AEP.

With these people the actual problem is not the increased blood sugar level, but the consequences resulting from it. Excessive levels of glucose will produce unacceptable sugar deposits in numerous structures of the organism ranging from the red blood hemoglobin to the cell membranes such as of the vessel and capillary systems. It is the resulting degeneration of the small vessels, especially, that can turn blood sugar levels into a severe problem that will often not surface until after twenty or thirty years.

We have observed in 24 years of administering 2-AEP (found in Membrane Integrity Factor™), to those with blood sugar problems, that this is extremely effective in retaining the function of the retina.

The kidneys as well are apparently protected in a manner unimaginable up to now with the administration of 2-AEP®. It is interesting that apparently there is not only a protective function, but initial forms of kidney damage, will disappear after a while when 2-AEP® (found in Membrane Integrity Factor™) is applied.

The use of the 2-AEP (in Membrane Integrity Factor™) has understandably given satisfaction to me and my collaborators. Dr. Morgan Raiford, Atlanta, Georgia, tirelessly emphasizes this great triumph at conventions in the U.S. The obvious control and early involution people given 2-AEP are a proud result of this research behind 2-AEP taken daily.

It is of great interest that the regulation of blood glucose levels within the normal range are supported by 2-AEP (in Membrane Integrity Factor™). For some people eat too many carbohydrates makes it hard to regulate the glucose transport into all cells. On the other hand, they do not eat, the blood sugar level declines too far, resulting in a craving for chocolate and concentrated carbohydrates. When given 2-AEP (in Membrane Integrity Factor™), this phenomenon practically disappears, obviously because the cell membrane-bonded regulation of the cells can return to greater normality. This phenomenon is of great interest, scientifically speaking.

The discovery of 2-AEP’s ability to support blood sugar levels already in the normal range is a source of some pride to me and my collaborators. Have you any idea of the gigantic number of people, especially in the civilized world, who seriously has to count on a reduced life-span because of their blood sugar? In this area, the use of 2-AEP (found in Membrane Integrity Factor™) would mean a preventative and protective discovery in the best sense of the word.

Electromagnetic Forces
Do you know how long approximately the entire human vessel and capillary system is? Estimates vary between 40,000 and 50,000 kilometers. You will wonder how a small human heart can pump the blood through such an immensely long and intertwined arterial system with relatively minimal power. The admirable answer is demonstrated on the testing grounds of the company Messerschmitt-Bolkow-Blohm. Their magnetic train is suspended and moved by an electromagnetic cushion, practically without friction. This is exactly how it works with the red blood particles which are larger than the diameter of the smallest capillaries. The blood particles then must momentarily "slim down" to squeeze through the passage.

During the last 24 years, we have been able to observe that for people taking 2-AEP (found in Membrane Integrity Factor™), circulation problems and the progression of varicose veins is almost entirely eliminated.

This is surely related to the fact that by taking 2-AEP (in Membrane Integrity Factor™), the condenser functions of the cell membrane systems are repaired and maintained at an optimal level. This is true even for older people. Naturally, this is accompanied by genuine youthfulness of the biological frame and certainly a substantially-increased life span.

2-AEP® is also remarkably effective against damage from extreme exposure to the sun, in particular, sunburn. Fortunately, cell aging caused by exceedingly strong light and UV radiation is prevented, or at least contained, by taking 2-AEP®. This would mean that a longer life span could be attained for people living in sunny zones of the earth.

A New Vitamin
Lately, we have often asked ourselves the question whether or not 2-AEP (in Membrane Integrity Factor™), should be designated as vitamins, or as an "essential nutrient" (indispensable nutrition factor). Dr. Don R. Davis, scientist at the renowned Clayton Foundation Biochemical Institute at The University of Texas, Austin, Texas, defines vitamins as such substances that a) are dispensable for the organism, and b) must be introduced from outside since they are not created by the organism.

At the convention at the Waldorf Astoria at the end of June 1987, I proposed to name the new metabolic 2-AEP "the membrane-integrity factor".

Since then it appears that the term "membrane integrity factor" was well chosen and lucid enough, so that both physicians and educated laymen get an understanding of the function of this new vitamin. 2-AEP will be important for significant progress in protective and preventative nutrients.

Hans A. Nieper, M.D.
Director, Dept. of Medicine
Paracelsus Silbersee Hospital

What is 2-AEP?
Membrane Integrity Factor's primary ingredient, 2-AEP, is the actual biochemical component making up the outer cell membranes of your body. Membrane Integrity Factor delivers 2-AEP directly to the outer cell walls to strengthen, seal, and protect your healthy cells and to repair your damaged cells. "This rejuvenation of your cells slows the aging process."

What is HGHR?
Human Growth Hormone (HGH) is an endocrine hormone that is produced by the pituitary gland. By the time we approach 65 years of age, our pituitary gland is producing only 15% to 20% of the Human Growth Hormone it did when we were teenagers! Human Growth Hormone Releaser (HGHR) is the substance that naturally increases your body's production and release of HGH through the pituitary gland. This is the safest, most natural method of giving your body HGH. Documented tests have shown that by naturally releasing the HGH through the pituitary gland, the biological clock can be reversed by many years.

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